What was the primary factor responsible for the anti-obesity effect observed in mice fed a high-fat diet supplemented with 15% whole Adzuki bean?

Answer

Reduced energy efficiency

Research conducted on mice consuming a high-fat diet supplemented with whole Adzuki beans revealed an interesting mechanism for managing weight gain. The protective effect was not achieved by making the mice eat less food or by blocking the absorption of fat; rather, the supplementation actively interfered with how the body processed the calories consumed. Specifically, the Adzuki beans significantly reduced the mice's energy efficiency, meaning that a larger proportion of the calories they did eat were not successfully converted into stored body fat, suggesting a fundamental metabolic shift in energy handling.

What was the primary factor responsible for the anti-obesity effect observed in mice fed a high-fat diet supplemented with 15% whole Adzuki bean?
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