Antioxidant compounds in artichokes modulate which critical signaling pathway to increase protective enzymes?
Answer
Nrf2 signaling pathway
The sophisticated action of artichoke antioxidants involves more than just scavenging free radicals; they actively regulate critical intracellular mechanisms. Specifically, these compounds are capable of modulating the Nrf2 signaling pathway. When this pathway is regulated effectively, it triggers a cellular response that leads to the increased internal production of the body's own protective enzymes, such as catalase (CAT) and glutathione peroxidase (GPx), enhancing overall cellular defense against oxidative stress.
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