Which protein found in potatoes stimulates the release of cholecystokinin (CCK) to promote satiety?
Answer
Potato proteinase inhibitor 2 (PI2)
The feeling of fullness, or satiety, promoted by potatoes, especially when eaten prepared healthily, is partially linked to a specific compound called potato proteinase inhibitor 2 (PI2). This protein has been identified as having the physiological effect of stimulating the release of cholecystokinin (CCK). CCK is recognized as a critical hormone that signals to the brain that the body is satisfied, thereby helping to curb subsequent hunger pangs and cravings. This mechanism contributes significantly to the potato's high ranking on satiety scales when compared against many other common food items.
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