Which human digestive enzyme is noted as unable to break down the indigestible wax esters in oilfish flesh?

Answer

Lipase

The inability of the human body to process the oils in fish like escolar is directly linked to the specific digestive enzyme responsible for fat breakdown. That enzyme is lipase, which is primarily secreted to hydrolyze triglycerides into absorbable components. However, lipase is ineffective or largely incapable of breaking down the molecular structure of wax esters, which comprise the majority of the problematic oil content in these fish species. Because lipase cannot cleave these long-chain esters into their constituent parts, the material remains undigested, bypasses absorption in the small intestine, and travels intact to the lower digestive tract where it causes symptomatic release.

Which human digestive enzyme is noted as unable to break down the indigestible wax esters in oilfish flesh?
consumptioneffectsymptomdigestionoilfish