Which key enzyme in the cholesterol synthesis pathway is inhibited *in vitro* by specific lipids like MGDGs and DGDGs isolated from taro flour derivatives?

Answer

Human lanosterol synthase

Taro demonstrates a multifaceted impact on heart health, extending beyond potassium and fiber to include specific lipid-modulating compounds found in its flour derivatives. Research has shown that certain lipids extracted from taro, namely monogalactosyldiacylglycerols (MGDGs) and digalactosyldiacylglycerols (DGDGs), exhibit an ability to inhibit human lanosterol synthase when tested *in vitro*. Lanosterol synthase holds a significant role because it is a critical enzyme in the pathway responsible for cholesterol synthesis within the body. Targeting this enzyme is a common molecular strategy utilized by pharmaceutical agents designed to manage high cholesterol, indicating a natural pathway in taro that supports healthy lipid management.

Which key enzyme in the cholesterol synthesis pathway is inhibited *in vitro* by specific lipids like MGDGs and DGDGs isolated from taro flour derivatives?

Related Questions

What is the scientific name for Taro, which originated in Southeast Asia, and is known as kalo in Hawaiian tradition?How does the Dietary Fiber content in a standard one-cup serving of cooked taro root compare quantitatively to an equivalent serving of potatoes?In cooked taro root, what percentage of the total starch content is constituted by the metabolically beneficial Resistant Starch (RS) variety?What essential compounds are produced in the colon when gut microbiota ferment undigested Resistant Starch and fiber from taro?Which enzyme's activity is inhibited by Proteins A-1 and B-2 found in defatted taro flour to help restore normal glucose levels in animal models?Which key enzyme in the cholesterol synthesis pathway is inhibited *in vitro* by specific lipids like MGDGs and DGDGs isolated from taro flour derivatives?How does the lectin **tarin** modulate the immune response by affecting the inflammatory mediator $ ext{PGE}_2$ to exert its anti-inflammatory action?What critical preparation step is mandatory for consuming taro root or leaves to deactivate the naturally occurring calcium oxalate crystals?What high percentage of the Daily Value for Vitamin A is supplied by a cooked cup of nutritious taro leaves, which also contain notable amounts of Vitamin C?Which process, involving the fermentation of taro corms, is suggested to potentially optimize the release or stability of certain beneficial compounds for improved absorption over immediate consumption?
healthbenefitrootvegetabletaro