Which enzyme's activity is inhibited by Proteins A-1 and B-2 found in defatted taro flour to help restore normal glucose levels in animal models?
Answer
$ ext{alpha}$-amylase
Taro exhibits anti-hyperglycemic properties partially attributed to specific compounds present within it, demonstrated in animal models where taro flour helped restore normal glucose levels in hyperglycemic rats. The mechanism involves specific inhibitory proteins identified within defatted taro flour, namely Protein A-1 and Protein B-2. These proteins function by actively inhibiting the activity of $ ext{alpha}$-amylase. Alpha-amylase is the key enzyme responsible for breaking down starches in the digestive process; by inhibiting it, the breakdown rate of starches is slowed, which contributes to the observed control over blood sugar.
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