How does stinging nettle extract reportedly interfere with classic hay fever symptoms?

Answer

It inhibits the release of histamine by blocking the receptors that histamine binds to.

The mechanism by which stinging nettle manages seasonal allergy symptoms involves interfering directly with the inflammatory cascade triggered by allergens. Specifically, the extract acts to inhibit the release of histamine, which is the primary chemical mediator responsible for classic allergic responses such as sneezing and a runny nose. Crucially, this action is achieved by nettle compounds blocking the specific receptors where histamine would normally bind, effectively dampening the entire subsequent reaction.

How does stinging nettle extract reportedly interfere with classic hay fever symptoms?
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