How do the two primary methods for using nettle for joint health differ in their mechanism of action?

Ingestion aims to reduce systemic inflammation, while topical application often relies on causing a mild counter-irritation to distract from deep joint pain.

When utilizing stinging nettle to support joint comfort, users often employ two distinct approaches, each leveraging different biochemical pathways. The method of ingestion, typically through teas or tinctures, is designed to target and reduce systemic inflammation throughout the body. In contrast, the traditional method involving topical application often requires carefully pressing or crushing the leaves lightly to release sap and applying them directly to the painful joint area. This topical approach functions by inducing a mild counter-irritation on the skin, which serves to temporarily divert attention away from underlying, deeper joint pain.