What specific action has the U.S. Food and Drug Administration (FDA) advised against concerning borage leaves and flowers?
Answer
Consuming them regularly or in large quantities
Due to the presence of hepatotoxic Pyrrolizidine Alkaloids (PAs) in the raw plant material, the U.S. Food and Drug Administration (FDA) has issued clear guidance regarding the consumption of borage leaves and flowers. The specific advisory is directed against ingesting these parts of the plant regularly or in significant doses, as this increases the risk of liver toxicity associated with the alkaloids. Although traditional methods sometimes involve cooking the leaves, which may reduce PA levels, the inherent risk remains substantial enough that reputable sources often recommend caution or outright avoidance of routine consumption of the raw herb material.

Related Questions
What is the primary beneficial fatty acid concentrated in borage seed oil associated with anti-inflammatory effects?Which skin condition is most studied regarding borage seed oil's application due to GLA deficiencies in inflamed skin?Which compounds found in raw borage leaves and flowers are known to be toxic to the liver upon ingestion?What distinct flavor profile do the fresh leaves of the borage plant offer when used culinarily?Borage seed oil provides a direct, rich source of GLA, bypassing the body's potentially challenging conversion from which precursor fatty acid?What specific action has the U.S. Food and Drug Administration (FDA) advised against concerning borage leaves and flowers?Individuals taking anticoagulant or antiplatelet medications must consult a provider before using borage oil because GLA might increase the risk of what?GLA functions as a precursor to which compound involved in regulating inflammatory processes in the body?What is the characteristic visual description of the vibrant blue flowers of *Borago officinalis*?Compared to skin health, why is scientific validation for using borage oil for hormonal support viewed with less certainty?What critical safety distinction exists between consuming commercial borage seed oil capsules and eating fresh leaves from the garden?