Individuals allergic to which family of plants should exercise caution regarding cross-reactivity with true anise (*Pimpinella anisum*)?
Answer
Apiaceae family
A critical safety consideration for consuming true anise involves potential cross-reactivity for individuals sensitive to other members of the Apiaceae family. Specific examples of related plants within this family that can cause cross-reactions include fennel, celery, and caraway. Due to this potential allergic linkage, careful sourcing and moderation are advised, particularly when using concentrated extracts, as high doses of the essential oil can pose toxicity risks generally.

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