What is the primary mechanism suggested for *G. asiatica*'s cognitive benefits observed in animal models?
Answer
Inhibiting the enzyme acetylcholinesterase (AChE)
The extract normalized the elevation of AChE caused by scopolamine. AChE breaks down acetylcholine, a key memory neurotransmitter; thus, inhibiting this enzyme supports cholinergic signaling.
Related Questions
Which part of the fresh *Grewia asiatica* fruit consistently exhibited the highest antioxidant activity in various solvent extractions?What is the primary mechanism suggested for *G. asiatica*'s cognitive benefits observed in animal models?In comparing the tall and dwarf varieties of *G. asiatica* developed in India, which characteristic is notably higher in the dwarf type?Which enzyme showed significantly stronger inhibitory activity (IC50 of $0.41 ext{ mg/mL}$) in ethanolic extracts compared to $\alpha$-amylase ($8.93 ext{ mg/mL}$)?What unexpected environmental remediation potential has been shown by extracts from the leaves and seeds of *G. asiatica*?How did the antipyretic activity of aqueous fruit extracts compare to aspirin in managing fever induced by *E. coli* endotoxin in rats?Which amino acids were identified as being present in the pulp and seeds, respectively?What effect did *G. asiatica* juice dilutions have on chemically induced memory impairment in the Passive Avoidance Test?What is the primary functional characteristic associated with the methanol extract of the fruit pomace?What is the primary family to which *Grewia asiatica* belongs, noted for being the sole genus within it that yields edible fruits?