Which inflammation-related gene expression in the liver tissue of mice fed a high-fat diet was effectively prevented from increasing by the inclusion of cloudberry supplementation?
Answer
Monocyte Chemoattractant Protein 1 (MCP1)
The study analyzing the genetic impacts of cloudberry supplementation on liver tissue showed that the berry powder effectively counteracted the inflammatory gene expression triggered by the high-fat diet. Specifically, the expression levels of Monocyte Chemoattractant Protein 1 (MCP1) were suppressed in the liver, remaining low similarly to the healthy state. MCP1 is noteworthy because it functions as a primary chemoattractant, signaling macrophages to infiltrate inflamed fat tissue, a process intimately associated with insulin resistance. Preventing its rise in the liver is a key anti-inflammatory mechanism shown by the cloudberry.
Related Questions
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